Case Study 6: Zachary's Story

Harlee Cheek
Case Study 6
Halstead

Unit 6 Case Study 1: Zachary's Story

A. An ulcer starts by eroding the mucosa of the G.I. tract wall. What functions of digestion and/or reabsorption might be lost if this layer is no longer functional? What functions will be compromised if the ulcer eats through the submucosa and then the muscularis?

-Absorption would not happen correctly some of the ingested and secreted may seep out of the lumen. This also could create a pathway of entry for pathogens if the ulcer ate through to the muscularis mucosa and also lose some control of defecation.

B. If Zachary has a peptic ulcer affecting his stomach or duodenum, which ...

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of lesions in the G.I. tract wall?

-Zachary's stomach contributes to the formation of ulcers in other parts of the G.I. tract by the acids needed to breakdown food are excessive and cause the stomach to over work therefore causing surrounding parts to be over worked as well. If the stomach is always churning food the digestion processes is always on going. Parietal cells (secrete HCI) and gastric glands (acetylcholine) are directly related to the formation of ulcers. A major causing factor is chronic inflammation due to Helicobacter pylori (H. pylori) that colonizes the mucosa. The immune system is unable to clear the infection, despite the appearance of antibodies. Thus, the bacterium can cause a chronic active gastritis. Gastrin stimulates the production of gastric acid by parietal cells. In H. pylori colonization responses to increased gastrin, the increase in acid can contribute to the erosion of the mucosa and therefore ulcer formation. Studies in the varying occurrence ...

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PAPER DETAILS

Added: 11/1/2015 12:45:48 PM
Submitted By: brtc2525
Category: Health & Medicine
Type: Premium Paper
Words: 1064
Pages: 4

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