Dna Replication

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This strand grows inward towards the replication fork as the DNA molecule unzips. This strand ends with a hydroxide (OH) group and is called the 3` prime or 3`end. The enzyme that catalyzes this process is called DNA polymerase.
The second strand is built by having a polymerase jump ahead on the strand and fill in the complementary nucleotides backwards. This strand moves in the outward direction, hence away from the replication fork. The DNA polymerase for this strand starts a burst of synthesis at the point of the replication fork. The addition of nucleotides to the 3` end of a short new chain until this new segment fills in a gap of 1000 to 2000 nucleotides between the replication fork and the end of the growing chain to which the previous segment was added. Hence, this new short chain is then added to the growing chain, and the polymerase jumps ahead again to fill in another gap. Thus in short, the polymerase copies the template strand in segments about 1000 nucleotides ...

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their paths to bent or diffract. The pattern created by the sum of total of these diffractions are then captured on a photographic film. The pattern is then interpreted into the image of the molecule through careful analysis. Thus, because of this research it led to the first theory and model structure of DNA.

MAURICE WILKENS

Maurice Wilkens was born in the year 1916 and is a British biochemist. Born in Pongaroa, New Zealand, he is currently the deputy director of biophysics research unit at the Medical Research Council. He attended the University of London from the years of 1955 to 1974 and was awarded the Noble Prize in 1962 for the discovery of the molecular structure of DNA.
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