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Endometriosis - Example Papers

Endometriosis

Etiology

The exact cause and pathogenesis of endometriosis is unclear. Several theories exist that attempt to explain this disease, although none have been entirely proven. [1] Leading theories include metaplastic conversion of coelomic epithelium and hematogenous or lymphatic dispersion of endometrial cells. It is likely a combination of various factors that cause and determine the severity of this disease.

Previous theories suggest that endometriosis results from the transport of viable endometrial cells through retrograde menstruation. Cells flow backward through the fallopian tubes and deposit on the pelvic organs, where they seed and grow. A population of cells resides in the ...

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may contribute to the early onset of endometriosis

Retrograde menstruation

Early in the 20th century (1927), Samson proposed his theory of retrograde menstruation through the fallopian tubes into the peritoneal cavity as a cause of endometriosis. Subsequent studies have shown that retrograde menstruation is a quite common physiologic event and cannot adequately explain the extrauterine implantation of endometrial tissue. Diagnostic laparoscopy during the perimenstrual period has shown that as many as 90% of women with patent fallopian tubes have bloody peritoneal fluid. Nonetheless, conditions that increase the rate of retrograde menstruation, such as congenital outflow tract obstructions, do increase the risk of endometriosis. Various animal experiments and clinical observations support this theory. [7, 8, 9, 10]

Because most women do not have endometriosis, perhaps immunologic or hormonal dysfunction leaves some women predisposed.

Immunologic ...

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Endometriosis. (2017, March 10). Retrieved August 1, 2025, from http://www.essayworld.com/essays/Endometriosis/106141

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PAPER DETAILS

Added: 3/10/2017 08:15:28 PM
Submitted By: yobalto
Category: Health & Medicine
Type: Premium Paper
Words: 1218
Pages: 5

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